At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https: //www.jnj.com

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Job Description:

Johnson & Johnson Innovative Medicine (J& J IM) develops treatments that improve the health of people worldwide. Research and development areas encompass cardiopulmonology, immunology, communicable diseases, neuroscience and oncology. Our goal is to help people live longer, healthier lives. We have produced and marketed many first-in-class prescription medications and are poised to serve the broad needs of the healthcare market – from patients to practitioners and from clinics to hospitals. To learn more about J& J Innovative Medicine, visit https: // https: //www.jnj.com/innovative-medicine.

We are looking for a Scientist / Senior Scientist in the department of Translational Pharmacokinetics/Pharmacodynamics and Investigative Toxicology (TPPIT) in Beerse, Belgium, to support small and large molecule drug discovery and development programs. Specifically, the candidate will be responsible for supporting a range of in vitro ADME assays (drug transporters, enzyme induction, drug metabolism, plasma and tissue binding, cell permeability and ad hoc mechanistic studies) and contribute to project progression and decision making by providing high quality data and expert opinion to multi-disciplinary project teams. In addition to project support, the candidate will have the opportunity to develop novel test systems and, in collaboration with biopharmaceutics teams, establish formulation-based delivery approaches to select molecules with a desired oral bioavailability.

We are a highly motivated team, and our laboratories are state-of-the-art. As part of the global Translational ADME community within TPPIT, you will have access to a large arsenal of in silico, in vitro and in vivo tools and the vast expertise of colleagues at our various research sites in Belgium and the United States.

Qualifications:

Education requirement:

• MSc in Pharmaceutical Sciences, Pharmacology, Biochemistry, Biomedical Sciences, Molecular Biology or a related field.

Experience and Skills

Required:

• Knowledge in DMPK relevant areas such as pharmacokinetics, in vitro ADME assays such as drug metabolism, drug transport, enzyme induction, cellular permeability, and protein and tissue binding.
• Ability to independently design, conduct, report and document experiments.
• Strong contributor to the team with excellent interpersonal, organizational, and oral/written communication skills.

Preferred:

• A PhD and/or prior industry experience in a relevant life science discipline will be considered for determining the job position level
• Experience in cell culture and characterization of recombinant cell lines and/or primary cells
• Hands-on experience in the characterization of (drug metabolizing) enzymes and/or transporters
• Interest/knowledge in quantitative mass spectrometry
• Interest/knowledge of oral delivery strategies for peptides/macromolecules, including the usage of absorption-enhancing excipients and lipid-based delivery systems
• A track record of scientific contributions, including peer reviewed publications and presentations, and/or patents.
• Excellent oral and written communication skills in English.

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.