At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https: //www.jnj.com

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Johnson & Johnson Innovative Medicine is recruiting for a Cell & Protein Engineering Summer 2025 Co-op, located in Spring House, PA.

Transcription/translation of GOI is influenced by many intrinsic proteins and regulatory elements in cell lines. It might be possible to modulate these controlling elements without enforcing metabolic engineering. To overcome transcriptional bottlenecks in antibody expression, we plan to implement an advanced gene regulation system in mammalian cell lines. This system, either constitutive or inducible, intends to precisely control the transcription of recombinant antibody expression cassettes, leveraging cutting-edge technology. This new technology will potentially allow for improving titers and critical quality attributes of antibodies in manufacturing CHO cell without targeted metabolic engineering and host cell line optimization.

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https: //www.jnj.com

The typical Co-op term is from June 2025 – December 2025.

Key Responsibilities:

• Develop and optimize cell culture techniques for Chinese Hamster Ovary (CHO) cells to produce recombinant proteins and biologics, focusing on enhancing antibody production.

• Utilize molecular biology techniques, such as gene editing and vector design, to engineer CHO cells for improved antibody expression and secretion.

• Conduct experiments to analyze and improve cell growth, productivity, and antibody titers through cell engineering and optimization of culture conditions.

• Perform routine cell culture maintenance, including subculturing, cryopreservation, and contamination monitoring, while applying best practices from molecular biology to enhance cell line stability.

• Collaborate with cross-functional teams to interpret experimental data and contribute to process development and scale-up strategies aimed at maximizing antibody yield and purity, ensuring compliance with industry regulations and quality standards in all laboratory procedures and documentation.

Other responsibilities include:

• Effectively present information/data both orally and in writing to diverse groups.

• Participation in technical discussions on design of experiments to fill gaps in knowledge.

• Execute experiments independently or in a team environment. Support miscellaneous laboratory work/training.

Qualifications

Education:

• Biology, Chemical Engineering, Biological Engineering, Biomedical Engineering, Molecular Biology, Microbiology, and related majors are preferred.

• Candidates must be actively enrolled in an accredited University for the duration of a co-op assignment pursuing a Master’s or PhD degree.

• Minimum GPA of 2.8 is required.

Experience and Skills

Required:

• Students with prior experience working in a molecular biology laboratory is required.

• Candidates must be legally authorized to work in the U.S.

• Ability to demonstrate strong analytical and quantitative skills is required.

• Excellent communication, presentation, and leadership skills are preferred.

• Ability to balance multiple projects and initiatives while executing results.

• Must be a self-starter works independently while contributing to the team goals.

• Proven leadership/participation with campus programs and/or community service activities is desired.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (ra-employeehealthsup@its.jnj.com) or contact AskGS to be directed to your accommodation resource.