At Genmab, we are dedicated to building extra[not]ordinary® futures, together, by developing antibody products and groundbreaking, knock-your-socks-off KYSO antibody medicines® that change lives and the future of cancer treatment and serious diseases. We strive to create, champion and maintain a global workplace where individuals' unique contributions are valued and drive innovative solutions to meet the needs of our patients, care partners, families and employees.

Our people are compassionate, candid, and purposeful, and our business is innovative and rooted in science. We believe that being proudly authentic and determined to be our best is essential to fulfilling our purpose. Yes, our work is incredibly serious and impactful, but we have big ambitions, bring a ton of care to pursuing them, and have a lot of fun while doing so.

Does this inspire you and feel like a fit? Then we would love to have you join us!

The Role

As the Manager, HR Effectiveness, you will serve as a highly trusted partner to and work closely with HR leaders across global commercialization. This role blends strategic coordination, operational excellence, program management, communications, and employee experience.

This role is ideal for someone who thrives in a fast-paced, highly matrixed environment and enjoys owning initiatives end-to-end with significant autonomy. You will operate as a "right hand" to Commercialization HR leadership-driving key people initiatives, orchestrating programs and events, ensuring operational excellence, and enabling leaders and teams to execute effectively at scale.

You will lead and coordinate a broad range of activities including employee engagement programs, recognition initiatives, onboarding experiences, talent processes, communications, reporting and analytics, special projects, and strategic HR operations support across a growing global organization.

This role requires exceptional organizational capability, strong judgment, executive presence, attention to detail, and the ability to independently navigate ambiguity while driving results and impact.

Key Responsibilities

• Lead and coordinate HR programs, initiatives, and strategic priorities across Global Commercialization, ensuring strong execution, stakeholder alignment, communication, and follow-through.

• Serve as a trusted partner to Commercialization HR leadership, translating business and people priorities into actionable plans and driving progress across a complex, matrixed global organization.

• Independently manage multiple projects and operational activities from planning through execution, proactively tracking milestones, dependencies, risks, decisions, and commitments to ensure successful outcomes.

• Act as a central point of coordination across HR Business Partners, Talent Acquisition, Centers of Excellence, and business leaders to drive alignment, communication, and execution of key people initiatives.

• Support and coordinate key HR processes, including talent reviews, engagement surveys, performance management, compensation cycles, workforce planning, organizational effectiveness initiatives, and reporting and analytics.

• Lead and support employee engagement, recognition, onboarding, leadership events, conferences, team experiences, and other initiatives that enhance employee experience and organizational culture.

• Develop executive-ready presentations, communications, dashboards, reports, briefing materials, and recommendations, synthesizing complex information into clear, concise, and actionable insights for leaders.

• Identify opportunities to improve processes, enhance operational effectiveness, leverage technology and AI-enabled tools, and drive continuous improvement across HR programs and workflows.

• Manage vendor relationships, budgets, purchase orders, invoices, travel, team events, and other operational activities supporting Commercialization HR initiatives.

• Build strong relationships across functions, geographies, and organizational levels while maintaining professionalism, discretion, sound judgment, and confidentiality in all interactions.

About You

• Bachelor's degree in Human Resources, Business Administration, Communications, Psychology, or a related field preferred, with 5+ years of progressive experience in HR, HR operations, program management, employee experience, talent operations, business operations, chief of staff, or related roles.

• Proven ability to operate independently, manage multiple complex projects simultaneously, and drive execution in a fast-paced, highly matrixed, global organization; experience in biotechnology, pharmaceutical, healthcare, or other highly regulated industries preferred.

• Demonstrated ability to translate ambiguous priorities into actionable plans, influence without authority, and successfully navigate competing priorities and stakeholder needs.

• Strong business acumen, judgment, and discretion, with the ability to handle sensitive and confidential matters professionally.

• Exceptional organizational, communication, stakeholder management, project coordination, and operational execution skills, with the ability to build trusted relationships and collaborate effectively across functions, levels, and geographies.

• Strong analytical, reporting, and problem-solving capabilities, including proficiency in Excel, PowerPoint, Workday, Microsoft 365, and related business tools.

• Experience developing executive-level presentations, communications, dashboards, and materials for senior leaders.

• Proactive, resourceful, and solutions-oriented, with a strong ownership mindset, attention to detail, and ability to thrive in ambiguity and dynamic environments.

• Experience leveraging AI-enabled productivity tools (e.g., Microsoft Copilot, ChatGPT, Claude) to enhance communication, analysis, project management, and operational effectiveness is a plus.

• Collaborative, low ego, and willing to roll up your sleeves while continuously seeking opportunities to improve processes, employee experience, and organizational impact.

Where You Will Work

This role is hybrid and based in Princeton, NJ.

For US based candidates, the proposed salary band for this position is as follows:

$89, 600.00---$134, 400.00

The actual salary offer will carefully consider a wide range of factors, including your skills, qualifications, experience, and location. Also, certain positions are eligible for additional forms of compensation, such as discretionary bonuses and long-term incentives.

When you join Genmab, you're joining a culture that supports your physical, financial, social, and emotional wellness. Within the first year, regular full-time U.S. employees are eligible for:

• 401(k) Plan: 100% match on the first 6% of contributions
• Health Benefits: Two medical plan options (including HDHP with HSA), dental, and vision insurance
• Voluntary Plans: Critical illness, accident, and hospital indemnity insurance
• Time Off: Paid vacation, sick leave, holidays, and 12 weeks of discretionary paid parental leave
• Support Resources: Access to child and adult backup care, family support programs, financial wellness tools, and emotional well-being support
• Additional Perks: Commuter benefits, tuition reimbursement, and a Lifestyle Spending Account for wellness and personal expenses

About Genmab

Genmab is an international biotechnology company with a core purpose to improve the lives of patients through innovative and differentiated antibody therapeutics. For 25 years, its hard-working, innovative and collaborative team has invented next-generation antibody technology platforms and harnessed translational, quantitative and data sciences, resulting in a proprietary pipeline including bispecific T-cell engagers, antibody-drug conjugates, next-generation immune checkpoint modulators and effector function-enhanced antibodies. By 2030, Genmab's vision is to transform the lives of people with cancer and other serious diseases with Knock-Your-Socks-Off (KYSO®) antibody medicines.

Established in 1999, Genmab is headquartered in Copenhagen, Denmark with international presence across North America, Europe and Asia Pacific. For more information, please visit Genmab.com and follow us on LinkedIn and X .

Genmab is committed to protecting your personal data and privacy. Please see our privacy policy for handling your data in connection with your application on our website Job Applicant Privacy Notice (genmab.com) .

Please note that if you are applying for a position in the Netherlands, Genmab's policy for all permanently budgeted hires in NL is initially to offer a fixed-term employment contract for a year, if the employee performs well and if the business conditions do not change, renewal for an indefinite term may be considered after the fixed-term employment contract.